BDBM13062 (4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl)methyl}phenyl) sulfamate::DASI Inhibitor 7::JMC514226 Compound 3

SMILES NS(=O)(=O)Oc1ccc(cc1)C(c1ccc(OS(N)(=O)=O)cc1)n1cncn1

InChI Key InChIKey=NOCLDVNYMUPLRM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 13062   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50:  22nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: >1.00E+4nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50:  3.04E+3nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of aromatase (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione as substrate after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University of Bath

LigandPNGBDBM13062((4-{[4-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of STS activity (unknown origin) expressed in JEG-3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed