BDBM13308 N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-1H-imidazole-4-sulfonamide::N-benzyl-N-{2-[(4-bromophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino]ethyl}-1-methyl-1H-imidazole-4-sulfonamide::Sulfonamide 12b

SMILES Cn1cnc(c1)S(=O)(=O)N(CCN(Cc1cncn1C)c1ccc(Br)cc1)Cc1ccccc1

InChI Key InChIKey=IJCDWDJDJPZXSX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 13308   

TargetATP-dependent RNA helicase RhlE(Plasmodium falciparum (malaria parasite P. falcipa...)
Yale University

LigandPNGBDBM13308(N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidaz...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13308(N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidaz...)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13308(N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidaz...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13308(N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13308(N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidaz...)
Affinity DataIC50:  530nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM13308(N-benzyl-N-(2-{(4-bromophenyl)[(1-methyl-1H-imidaz...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed