BDBM13409 3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-cyanophenyl)(1,2-dimethyl-1H-imidazol-5-yl)methoxy]methyl}benzonitrile::A313326 Analogue 53

SMILES Cc1ncc(C(OCc2ccc(cc2-c2ccc3OCOc3c2)C#N)c2ccc(cc2)C#N)n1C

InChI Key InChIKey=KLNLNTKIKMROQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13409   

TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Globe Pharmaceutical R and Abbott Laboratories

LigandPNGBDBM13409(3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-cyanophenyl)(1,...)
Affinity DataIC50:  1.60nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM13409(3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-cyanophenyl)(1,...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bos taurus (bovine))
Globe Pharmaceutical R and Abbott Laboratories

LigandPNGBDBM13409(3-(2H-1,3-benzodioxol-5-yl)-4-{[(4-cyanophenyl)(1,...)
Affinity DataIC50:  4.70E+3nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed