BDBM13410 3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1,3-thiazol-5-yl)methoxy]methyl}benzonitrile::A313326 Analogue 54

SMILES Clc1cccc(c1)-c1cc(ccc1COC(c1cncs1)c1ccc(cc1)C#N)C#N

InChI Key InChIKey=LFEQCNDTFILPLL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13410   

TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Globe Pharmaceutical R and Abbott Laboratories

LigandPNGBDBM13410(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1,3-thiazol...)
Affinity DataIC50:  4nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
The M.S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM13410(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1,3-thiazol...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of FTaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Bos taurus (bovine))
Globe Pharmaceutical R and Abbott Laboratories

LigandPNGBDBM13410(3-(3-chlorophenyl)-4-{[(4-cyanophenyl)(1,3-thiazol...)
Affinity DataIC50: >1.00E+4nMAssay Description:The in vitro activity of compounds inhibiting FTase or GGTase-I was determined by using scintillation proximity assay (SPA) technology. The assays we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed