BDBM13545 N'-(1,2,3,4-tetrahydroacridin-9-yl)-3-(3,4,5-trimethoxyphenyl)propanehydrazide::N-1,2,3,4-Tetrahydroacridin-9-yl-3-(3,4,5-trimethoxyphenyl)propanohydrazide::tacrine derivative 16a
SMILES COc1cc(CCC(=O)NNc2c3CCCCc3nc3ccccc23)cc(OC)c1OC
InChI Key InChIKey=ZIHQIMALTYQRGD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 13545
Affinity DataIC50: 365nMpH: 7.3 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Rheinische Friedrich-Wilhelms-Universitat Bonn
Rheinische Friedrich-Wilhelms-Universitat Bonn
Affinity DataIC50: 294nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Rheinische Friedrich-Wilhelms-Universitat Bonn
Rheinische Friedrich-Wilhelms-Universitat Bonn
Affinity DataIC50: 40.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair
Affinity DataIC50: 12.1nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changed at 412 nm and was monitored with spectr...More data for this Ligand-Target Pair