BDBM13821 3-amidinobenzylindole carboxamide 5::3-bromo-N,1-bis[(3-carbamimidoylphenyl)methyl]-4-methyl-1H-indole-2-carboxamide

SMILES Cc1cccc2n(Cc3cccc(c3)C(N)=N)c(C(=O)NCc3cccc(c3)C(N)=N)c(Br)c12

InChI Key InChIKey=JBQWITKJQABBAY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13821   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM13821(3-amidinobenzylindole carboxamide 5 | 3-bromo-N,1-...)
Affinity DataKi:  50nM ΔG°:  -9.95kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM13821(3-amidinobenzylindole carboxamide 5 | 3-bromo-N,1-...)
Affinity DataKi:  2.07E+3nM ΔG°:  -7.75kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed