BDBM13822 3-amidinobenzylindole carboxamide 6::3-bromo-N,1-bis[(3-carbamimidoylphenyl)methyl]-1H-indole-2-carboxamide

SMILES NC(=N)c1cccc(CNC(=O)c2c(Br)c3ccccc3n2Cc2cccc(c2)C(N)=N)c1

InChI Key InChIKey=NVOVMNVSNWBIRX-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13822   

TargetCoagulation factor X(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM13822(3-amidinobenzylindole carboxamide 6 | 3-bromo-N,1-...)
Affinity DataKi:  26nM ΔG°:  -10.3kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Aventis Pharma Deutschland

LigandPNGBDBM13822(3-amidinobenzylindole carboxamide 6 | 3-bromo-N,1-...)
Affinity DataKi:  3.29E+3nM ΔG°:  -7.47kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed