BDBM139376 US8889671, 5

SMILES C[C@H]1COC(=O)N1c1noc2c(F)c3N4C[C@@H](C)O[C@@H](C)[C@@H]4C4(Cc3cc12)C(=O)NC(=O)NC4=O

InChI Key InChIKey=ZSWMIFNWDQEXDT-ZESJGQACSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139376   

TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Astrazeneca

US Patent
LigandPNGBDBM139376(US8889671, 5)
Affinity DataIC50:  169nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM139376(US8889671, 5)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
University Of Cape Town

Curated by ChEMBL
LigandPNGBDBM139376(US8889671, 5)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Staphylococcus aureus ATTC 25923 DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed