BDBM142255 US8933099, 21

SMILES CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(cc4)C4CCN(C)CC4)c3)c(OCCOC)cc12

InChI Key InChIKey=PVPYYKGOLJMILD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142255   

TargetFibroblast growth factor 2(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM142255(US8933099, 21)
Affinity DataIC50:  5.10nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR2 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM142255(US8933099, 21)
Affinity DataIC50:  5.70nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR1 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM142255(US8933099, 21)
Affinity DataIC50:  683nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR4 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM142255(US8933099, 21)
Affinity DataIC50:  6nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR3 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In DepthDetails US Patent