BDBM14230 5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),4,9,11-pentaene-4-carboxylic acid::thienobenzothiophene 20

SMILES OC(=O)COc1c(sc2c1sc1ccccc21)C(O)=O

InChI Key InChIKey=NGSARUJAKPRRDR-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 14230   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of PTPN1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi:  4.10E+3nM ΔG°:  -7.34kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibition of PTPN2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi:  9.20E+3nM ΔG°:  -6.87kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition of PTPRFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Miami

Curated by ChEMBL
LigandPNGBDBM14230(5-(carboxymethoxy)-3,7-dithiatricyclo[6.4.0.0^{2,6...)
Affinity DataKi: >1.25E+6nMAssay Description:Inhibition of PTPRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed