BDBM14263 4-bromo-3-(carboxymethoxy)-5-(4-{methyl[4-(trifluoromethyl)benzene]sulfonamido}phenyl)thiophene-2-carboxylic acid::Monocyclic thiophene analog 32

SMILES CN(c1ccc(cc1)-c1sc(C(O)=O)c(OCC(O)=O)c1Br)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=XZXRRLCYZMHHQT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14263   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14263(4-bromo-3-(carboxymethoxy)-5-(4-{methyl[4-(trifluo...)
Affinity DataKi:  1.20E+3nM ΔG°:  -8.07kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed