BDBM142746 US8937193, 8a
SMILES CC(CNC(=O)c1c(O)c(O)cc2c1c(=O)c(C)c(-c1c(C)c(=O)c3c(C(=O)NCC(C)c4ccccc4)c(O)c(O)cc3c1=O)c2=O)c1ccccc1
InChI Key InChIKey=BBLHWQAOYOUAEN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 142746
Affinity DataIC50: 320nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataIC50: 470nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
TargetBcl-2-related protein A1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataIC50: 710nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute
US Patent
Sanford-Burnham Medical Research Institute
US Patent
Affinity DataIC50: 230nMT: 2°CAssay Description:A Bak BH3 peptide (F-BakBH3) (GQVGRQLAIIGDDINR (SEQ ID NO:1)) was labeled at the N-terminus with fluorescein isothiocyanate (FITC) (Molecular Probes)...More data for this Ligand-Target Pair