BDBM143199 US11040980, Example 19::US8940744, 19::US9266895, 19::US9994576, 19

SMILES CC(C)(\C=C(/C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3ccccc3)cc2F)c2c(N)ncnc12)N1CC2(COC2)C1

InChI Key InChIKey=XTBYTIMEUSLGIH-CLMUKVTESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 143199   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM143199(US11040980, Example 19 | US8940744, 19 | US9266895...)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM143199(US11040980, Example 19 | US8940744, 19 | US9266895...)
Affinity DataIC50:  1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM143199(US11040980, Example 19 | US8940744, 19 | US9266895...)
Affinity DataIC50:  1.5nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM143199(US11040980, Example 19 | US8940744, 19 | US9266895...)
Affinity DataIC50:  1.5nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In DepthDetails US Patent