BDBM14320 1-amino-isoquinoline::CHEMBL62083::Fragment 17::fragment 1 (J. med. chem.,50,1116)::isoquinolin-1-amine

SMILES Nc1nccc2ccccc12

InChI Key InChIKey=OSILBMSORKFRTB-UHFFFAOYSA-N

Data  5 KI  4 IC50  2 Kd  1 Other

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14320   

TargetTryptase beta-2(Homo sapiens (Human))
Celera

LigandPNGBDBM14320(1-amino-isoquinoline | CHEMBL62083 | Fragment 17 |...)
Affinity DataKi:  3.90E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14320(1-amino-isoquinoline | CHEMBL62083 | Fragment 17 |...)
Affinity DataKi:  6.00E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed