BDBM14330 2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bromo-4-methylbenzen-1-olate::CRA-9076

SMILES Cc1cc(Br)c([O-])c(c1)-c1cc2cc(ccc2[nH]1)C(N)=[NH2+]

InChI Key InChIKey=BVTBOJXEAPSOEB-UHFFFAOYSA-N

Data  5 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14330   

TargetCoagulation factor X(Homo sapiens (Human))
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  43nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  50nM ΔG°:  -9.85kcal/molepH: 7.02 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  64nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  140nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Celera

LigandPNGBDBM14330(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-6-bro...)
Affinity DataKi:  460nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed