BDBM143695 US9682959, 3::US9751856, 3

SMILES CN1C(=O)C(C)(C)N=C1c1ccc(cn1)C#Cc1cccc(Cl)c1

InChI Key InChIKey=OQPPLJFHCIDVDV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143695   

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143695(US9682959, 3 | US9751856, 3)
Affinity DataKi:  16nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143695(US9682959, 3 | US9751856, 3)
Affinity DataKi:  16nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent