BDBM143794 US10183953, Example 55::US8969352, 55::US9611277, Example 55::US9845333, 55

SMILES Cc1cccc(C(=O)N2CC3CC(Nc4ccc(cn4)C(F)(F)F)C2C3)c1-n1nccn1

InChI Key InChIKey=TWMWEJVSFZPUFN-UHFFFAOYSA-N

Data  18 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 143794   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM143794(US10183953, Example 55 | US8969352, 55 | US9611277...)
Affinity DataKi:  3nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
TBA

US Patent
LigandPNGBDBM143794(US10183953, Example 55 | US8969352, 55 | US9611277...)
Affinity DataKi:  3nMAssay Description:Rat and Human Orexin 1 Receptor:Human Embryonic Kidney 293 cells (HEK293) stably expressing rat orexin 1 receptor (Genebank accession number NM_00152...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin receptor type 2(Rattus norvegicus (Rat))
TBA

US Patent
LigandPNGBDBM143794(US10183953, Example 55 | US8969352, 55 | US9611277...)
Affinity DataKi:  46nMAssay Description:Human Orexin 2 Receptor:HEK293 stably expressing human orexin 2 receptor (Genebank accession number NM_001526) were grown to confluency in DMEM (Hycl...More data for this Ligand-Target Pair
In DepthDetails US Patent