BDBM144346 US8969348, 2-{4-[(1,4-Dimethyl-1H-indol-3-yl)methyl]-1-oxophthalazin-2(1H)-yl}pentanoic acid

SMILES CCCC(C(O)=O)n1nc(Cc2cn(C)c3cccc(C)c23)c2ccccc2c1=O

InChI Key InChIKey=CFWPPIWGODXVHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144346   

TargetChymase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM144346(US8969348, 2-{4-[(1,4-Dimethyl-1H-indol-3-yl)methy...)
Affinity DataIC50:  9nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In DepthDetails US Patent