BDBM14694 2-(carboxymethyl)-5-[(2S)-2-acetamido-2-{[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]carbamoyl}ethyl]benzoic acid::5-[(2S)-2-(acetylamino)-3-{[(3S)-1-(biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]amino}-3-oxopropyl]-2-(carboxymethyl)benzoic acid::CHEMBL432359::Inhibitor 6::RU85053

SMILES CC(=O)N[C@@H](Cc1ccc(CC(O)=O)c(c1)C(O)=O)C(=O)N[C@H]1CCCCN(Cc2ccc(cc2)-c2ccccc2)C1=O

InChI Key InChIKey=CEKLBQMULVLLTD-VMPREFPWSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 14694   

TargetProto-oncogene tyrosine-protein kinase Src [145-252](Homo sapiens (Human))
Aventis Pharma

LigandPNGBDBM14694(2-(carboxymethyl)-5-[(2S)-2-acetamido-2-{[(3S)-2-o...)
Affinity DataIC50:  450nMAssay Description:SPA uses 125I as energy donor and scintillant-coated beads as energy acceptor. The labeled ligand is captured by the biotinylated Src-SH2 protein imm...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM14694(2-(carboxymethyl)-5-[(2S)-2-acetamido-2-{[(3S)-2-o...)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration against SH2 domain of human p60 Src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM14694(2-(carboxymethyl)-5-[(2S)-2-acetamido-2-{[(3S)-2-o...)
Affinity DataIC50:  450nMAssay Description:Binding affinity towards Src protein tryrosine kinase SH2 domain using surface plasmon resonance (SPR) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed