BDBM147465 US8957219, II-1-17

SMILES CN(C)C(=O)c1cccc(CNC(=O)Cc2nc3ccc(cc3s2)-c2ccccc2)c1

InChI Key InChIKey=VNRZOXHKJSIGMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 147465   

TargetEndothelial lipase(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM147465(US8957219, II-1-17)
Affinity DataIC50:  1.30E+3nMT: 2°CAssay Description:After the present compound dissolved in DMSO was added to become 0.5% DMSO to the reaction buffer consisting of 20 mM tris hydrochloric acid (pH7.4),...More data for this Ligand-Target Pair
In DepthDetails US Patent