BDBM149984 US8975417, 40
SMILES Cn1cc(cc(Cl)c1=O)N1C(c2c(nn(C3CC3)c2C(F)(F)F)C1=O)c1ccc(Cl)cc1
InChI Key InChIKey=CPMTVMSTJKIGJI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 149984
Affinity DataIC50: 740nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair