BDBM150006 US8975417, 62

SMILES COc1ncc(c(OC)n1)-n1nc2C(=O)N([C@@H](c2c1C(C)C)c1ccc(Cl)cc1)c1cc(C)c2onc(C)c2c1

InChI Key InChIKey=BNWMHKNZCUUJMF-RUZDIDTESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 150006   

TargetCREB-binding protein(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM150006(US8975417, 62)
Affinity DataIC50:  1.70E+3nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM150006(US8975417, 62)
Affinity DataIC50:  72nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM150006(US8975417, 62)
Affinity DataIC50:  60nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM150006(US8975417, 62)
Affinity DataIC50:  67nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
In DepthDetails US Patent