BDBM150060 US8975417, 120
SMILES Cc1nn(-c2ccnn2C)c2C(=O)N([C@@H](c12)c1ccc(Cl)cc1)c1cc(C)c(=O)n(C)c1
InChI Key InChIKey=LCXHXIMNUYTCEI-HXUWFJFHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 150060
Affinity DataIC50: 83nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:All assays were performed in 384-well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMpH: 7.5 T: 2°CAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair