BDBM15011 2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicarboxylate::Pyrrole Analogue 1

SMILES CCOC(=O)c1[nH]c(C=O)c(C(=O)OCC)c1C

InChI Key InChIKey=WPKKEQCPXUTCDZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15011   

TargetInsulin receptor(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15011(2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicar...)
Affinity DataIC50:  1.20E+4nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistidine biosynthesis bifunctional protein HisB(Escherichia coli (strain K12))
Monsanto

Curated by ChEMBL
LigandPNGBDBM15011(2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicar...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Escherichia coli imidazoleglycerol phosphate dehydratase using imidazole glycerol phosphate as substrate incubated for 30 min prior to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15011(2,4-diethyl 5-formyl-3-methyl-1H-pyrrole-2,4-dicar...)
Affinity DataIC50:  2.70E+3nMpH: 7.4 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate.HTRF is based on the proximity of europium cryptate (donor fluorophore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed