BDBM151315 BDBM151471::US8987314, B113

SMILES COCCNC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=OEXUPJCONPLVRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 151315   

TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151315(BDBM151471 | US8987314, B113)
Affinity DataIC50:  0.700nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151315(BDBM151471 | US8987314, B113)
Affinity DataIC50:  306nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151315(BDBM151471 | US8987314, B113)
Affinity DataIC50:  48.2nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM151315(BDBM151471 | US8987314, B113)
Affinity DataIC50:  2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In DepthDetails US Patent