BDBM152274 US8993556, 5-[2,4-Dihydroxy-6-(4-nitrophenoxy)phenyl]-N-ethylisoxazole-3-carboxamide

SMILES CCNC(=O)c1cc(on1)-c1c(O)cc(O)cc1Oc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=DAESMMVDEWYEKZ-UHFFFAOYSA-N

Data  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 152274   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM152274(US8993556, 5-[2,4-Dihydroxy-6-(4-nitrophenoxy)phen...)
Affinity DataKd:  0.800nMpH: 7.6Assay Description:The evaluation of the binding affinity (KD) of the compounds of formula (I) to the HSP90 protein was done using Biacore T100.His-HSP90 N-term domain ...More data for this Ligand-Target Pair