BDBM15233 4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene-1-sulfonamide::alcohol-triazole 17::benzene sulfonamide 17

SMILES NS(=O)(=O)c1ccc(cc1)-n1cc(CO)nn1

InChI Key InChIKey=IIQIBRLYHGPETH-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 15233   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  8.10nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  48nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  134nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  235nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  873nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase AssayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM15233(4-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]benzene...)
Affinity DataKi:  6.20E+3nM ΔG°:  -7.10kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed