BDBM152722 N-{3-[(pyrrolidin-3-yloxy)methyl]phenyl}thiophene-2-carboximidamide (27)::US9242957, 9
SMILES N=C(Nc1cccc(COC2CCNC2)c1)c1cccs1
InChI Key InChIKey=OOJUYDKIKUNGMC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 152722
Affinity DataKi: 139nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
Affinity DataKi: 1.58E+4nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
Affinity DataKi: 3.65E+4nMAssay Description:The compounds were evaluated for in vitro inhibition against three NOS isozymes: rat nNOS, bovine eNOS and marine iNOS using known literature methods...More data for this Ligand-Target Pair
TargetNitric oxide synthase oxygenase(Bacillus subtilis (Firmicutes))
University of California Irvine
University of California Irvine
Affinity DataKd: 7.24E+4nMAssay Description:In short, the difference between the imidazole-bound low-spin peak at 430 nm and the inhibitorbound high-spin peak at 395 nm was measured as a functi...More data for this Ligand-Target Pair