BDBM152734 11-bromo-5-[4-(2-fluorophenyl)piperazine-1- carbonyl]-8,10-dithia-3,4- diazatricyclo[7.3.0.0,6]dodeca-1(9),2,5,11- tetraene (7c)

SMILES Fc1ccccc1N1CCN(CC1)C(=O)c1[nH]nc-2c1CSc1sc(Br)cc-21

InChI Key InChIKey=RBSGTEYUENESQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152734   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandPNGBDBM152734(11-bromo-5-[4-(2-fluorophenyl)piperazine-1- carbon...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Maharaja Ranjit Singh Punjab Technical University

Curated by ChEMBL
LigandPNGBDBM152734(11-bromo-5-[4-(2-fluorophenyl)piperazine-1- carbon...)
Affinity DataIC50:  5.70E+3nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed