BDBM15301 benzyl N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]carbamate::dihydropyridazinone 6d

SMILES CC1CC(=O)NN=C1c1ccc(NC(=O)OCc2ccccc2)cc1

InChI Key InChIKey=OYFKPUPGRGTQPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15301   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15301(benzyl N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyri...)
Affinity DataIC50:  2.90nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15301(benzyl N-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyri...)
Affinity DataIC50:  1nMpH: 7.5 T: 22°CAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed