BDBM15324 3-[(2-{[4-(4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)-3-methylphenyl]amino}-6-oxocyclohex-1-en-1-yl)methyl]benzonitrile::Aryldimethylpyrazolone 18c
SMILES Cc1cc(NC2=C(Cc3cccc(c3)C#N)C(=O)CCC2)ccc1C1=NNC(=O)C1(C)C
InChI Key InChIKey=HFPJOEDYSNNHMV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 15324
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112](Homo sapiens (Human))
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 130nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Homo sapiens (Human))
Merck Research Laboratories
Merck Research Laboratories
Affinity DataIC50: 10nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair