BDBM153319 BPH-1419
SMILES NCCc1cc(Br)cc(c1)C#Cc1ccc(cc1)C#Cc1cc(Br)cc(CCN)c1
InChI Key InChIKey=KBEUXQAMMSJKRE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 153319
TargetShort-chain Z-isoprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 4.40E+3nMAssay Description:The IC50 values for the most active hits were verified by radiometric assay as follows. A mixture of 15 µM cis-FPP, 100 nM DPPS, and inhibitors in th...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 570nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair