BDBM153331 BPH-1427

SMILES NCCc1cccc(c1)C#Cc1ccc(cc1)C#Cc1cccc(CCN)c1

InChI Key InChIKey=JXWAMFIRXRHOIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153331   

TargetShort-chain Z-isoprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego

LigandPNGBDBM153331(BPH-1427)
Affinity DataIC50:  1.90E+4nMAssay Description:The IC50 values for the most active hits were verified by radiometric assay as follows. A mixture of 15 µM cis-FPP, 100 nM DPPS, and inhibitors in th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego

LigandPNGBDBM153331(BPH-1427)
Affinity DataIC50:  3.20E+3nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed