BDBM153331 BPH-1427
SMILES NCCc1cccc(c1)C#Cc1ccc(cc1)C#Cc1cccc(CCN)c1
InChI Key InChIKey=JXWAMFIRXRHOIS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 153331
TargetShort-chain Z-isoprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 1.90E+4nMAssay Description:The IC50 values for the most active hits were verified by radiometric assay as follows. A mixture of 15 µM cis-FPP, 100 nM DPPS, and inhibitors in th...More data for this Ligand-Target Pair
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego
University of California San Diego
Affinity DataIC50: 3.20E+3nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair