BDBM15361 (1aR,2Z,4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione::(4R,6R,8R,9Z,11E)-16-chloro-17,19-dihydroxy-4-methyl-3,7-dioxatricyclo[13.4.0.0^{6,8}]nonadeca-1(19),9,11,15,17-pentaene-2,13-dione::CHEMBL414883::Microlactone, 1::Monorden::Radicicol

SMILES [H][C@@]12C[C@@H](C)OC(=O)c3c(O)cc(O)c(Cl)c3CC(=O)C=CC=C[C@@]1([H])O2

InChI Key InChIKey=WYZWZEOGROVVHK-DFKRKDTASA-N

Data  2 KI  6 IC50

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15361   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM15361((1aR,2Z,4E,14R,15aR)-8-chloro-9,11-dihydroxy-14-me...)
Affinity DataIC50:  150nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair