BDBM15566 (3S)-3-{[(3S)-3-fluoropyrrolidin-1-yl]carbonyl}-7-[3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-1,2,3,4-tetrahydroisoquinoline::DPP-4 ligand 8

SMILES F[C@H]1CCN(C1)C(=O)[C@@H]1Cc2ccc(cc2CN1)-c1cccc(c1)-c1nnn[nH]1

InChI Key InChIKey=XBWNUNHLYKHRFT-OALUTQOASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15566   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15566((3S)-3-{[(3S)-3-fluoropyrrolidin-1-yl]carbonyl}-7-...)
Affinity DataIC50:  310nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed