BDBM15570 (3R)-3-amino-4-[2,5-difluoro-4-(methylsulfanyl)phenyl]-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[3,4-a]pyrazin-7-yl]butan-1-one::DPP-4 ligand 12

SMILES CSc1cc(F)c(C[C@@H](N)CC(=O)N2CCn3c(C2)nnc3C(F)(F)F)cc1F

InChI Key InChIKey=MDSAWPXFBWPRLD-SNVBAGLBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15570   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15570((3R)-3-amino-4-[2,5-difluoro-4-(methylsulfanyl)phe...)
Affinity DataIC50:  780nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed