BDBM155929 US9018211, 55
SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCN(CC2CCc3c2ccc(F)c3[N+]#[C-])CC1
InChI Key InChIKey=RVDCSPMPHIFLNZ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 155929
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 23nMpH: 7.4Assay Description:Block of Kir 1.1 (ROMKl) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391 : 85- 100 (1981)) using the IonWork...More data for this Ligand-Target Pair