BDBM156437 US10118915, Compound 371::US9682966, 231::US9682966, 371

SMILES Cc1noc(n1)-c1cc2cc(C)ccc2nc1N1CCC(CC1)NC1CCCCC1O

InChI Key InChIKey=VKORYNIHEXANNO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 156437   

TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156437(US10118915, Compound 371 | US9682966, 231 | US9682...)
Affinity DataIC50:  0.860nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156437(US10118915, Compound 371 | US9682966, 231 | US9682...)
Affinity DataIC50:  1nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156437(US10118915, Compound 371 | US9682966, 231 | US9682...)
Affinity DataIC50:  0.860nMAssay Description:Well-known assay for kappa opioid receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM156437(US10118915, Compound 371 | US9682966, 231 | US9682...)
Affinity DataIC50:  1nMT: 2°CAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements. The carboxy terminus of the OPRK1 receptor has a 7 amino acid l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent