BDBM15754 (2S)-3-(3-{[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]carbonyl}phenoxy)propane-1,2-diol::5-Amino-1-(4-fluorophenyl)-4-[3-{2(S), 3-dihydroxypropoxy}benzoyl]pyrazole::CHEMBL203567::RO3201195::aminopyrazole 63
SMILES Nc1c(cnn1-c1ccc(F)cc1)C(=O)c1cccc(OC[C@@H](O)CO)c1
InChI Key InChIKey=IJDQETGUEUJVTB-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 15754
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
Affinity DataKd: 5.00E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of p38alpha in hTERT-immortalized human HCA2 cells assessed as decrease in phosphorylated HSP27 level by ELISA in presence of anisomycinMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of p38alpha (unknown origin)-mediated TNFalpha production in peripheral mononucleocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of p38alpha (unknown origin)-mediated IL1beta production in peripheral mononucleocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of p38alpha-induced TNFalpha production in human THP1 cellsMore data for this Ligand-Target Pair