BDBM158173 US9029360, 16

SMILES Cn1c2CCN(CCc2sc1=O)C(=O)c1cc2ncc(Br)cn2n1

InChI Key InChIKey=OGZNOTUYMHUJHG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158173   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158173(US9029360, 16)
Affinity DataIC50: >1.00E+4nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta -HSD1 was determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio international, France) detec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM158173(US9029360, 16)
Affinity DataIC50:  1.29E+3nMAssay Description:Activation of the mGluR5 receptor expressed in cell lines results in an increase in intracellular calcium concentration. Using calcium sensitive fluo...More data for this Ligand-Target Pair
In DepthDetails US Patent