BDBM159311 US10093663, Example 16::US9682968, Example-16

SMILES Cc1cc(C2CC2)c(CN2CCCC[C@H]2c2ccc(C(O)=O)c(F)c2)c2cc[nH]c12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159311   

TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM159311(US10093663, Example 16 | US9682968, Example-16)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetComplement factor B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM159311(US10093663, Example 16 | US9682968, Example-16)
Affinity DataIC50:  0.0300nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent