BDBM160802 US10167313, Compound 69::US9045524, 69

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)OCc1ccccc1)c1ccccc1)C(=O)N[C@@H](CC(O)=O)\C=C\S(=O)(=O)c1ccccc1

InChI Key InChIKey=XNKWERCTKCULEN-OPZJAVCUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 160802   

TargetCaspase-1(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160802(US10167313, Compound 69 | US9045524, 69)
Affinity DataIC50: >3.33E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-5(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160802(US10167313, Compound 69 | US9045524, 69)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-3(Homo sapiens (Human))
Genesis Technologies

US Patent
LigandPNGBDBM160802(US10167313, Compound 69 | US9045524, 69)
Affinity DataIC50:  100nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-9(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160802(US10167313, Compound 69 | US9045524, 69)
Affinity DataIC50: >3.33E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-3(Homo sapiens (Human))
Genesis Technologies

US Patent
LigandPNGBDBM160802(US10167313, Compound 69 | US9045524, 69)
Affinity DataIC50:  100nMAssay Description:To test the efficacy of caspase-3 inhibitors at the cellular level, the ability of selected compounds to inhibit the proteolytic cleavage of PARP (po...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCaspase-7(Homo sapiens (Human))
Novagenesis Foundation

US Patent
LigandPNGBDBM160802(US10167313, Compound 69 | US9045524, 69)
Affinity DataIC50:  1.80E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In DepthDetails US Patent