BDBM16189 4-(3-Iodophenyl)-3-oxobutanenitrile::beta-ketonitrile 5f

SMILES Ic1cccc(CC(=O)CC#N)c1

InChI Key InChIKey=KLMBVFZRVZAWFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16189   

TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
Bar-Ilan University

LigandPNGBDBM16189(4-(3-Iodophenyl)-3-oxobutanenitrile | beta-ketonit...)
Affinity DataIC50:  3.50E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [600-1159,L699I,K702N,C879S](Human immunodeficiency virus type 1)
Bar-Ilan University

LigandPNGBDBM16189(4-(3-Iodophenyl)-3-oxobutanenitrile | beta-ketonit...)
Affinity DataIC50:  9.40E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1159,Y780C]/Imidazoleglycerol-phosphate dehydratase [600-1029,Y780C](Human immunodeficiency virus type 1)
Bar-Ilan University

LigandPNGBDBM16189(4-(3-Iodophenyl)-3-oxobutanenitrile | beta-ketonit...)
Affinity DataIC50:  9.90E+3nMpH: 7.5 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed