BDBM162870 US9056859, 48

SMILES COc1cc(CC(=O)N2CCN(CCc3ccc4C(=O)OCc4c3C)CC2)c(F)cc1C#N

InChI Key InChIKey=OXSDIZZXQNBJOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162870   

TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162870(US9056859, 48)
Affinity DataIC50:  35nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In DepthDetails US Patent