BDBM163635 SR-3298::US10807944, Compound RLS2-225::US11731934, Compound RLS2-225

SMILES CN(C)c1ccc(cc1)C(=O)NNCC1CCCC1

InChI Key InChIKey=LJBJHPWKSLDVNC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 163635   

TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.76E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  3.25E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University Of Florida College Of Medicine

LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.67E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.76E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  3.25E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.67E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.76E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  3.25E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.67E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.76E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central C(O) NH NH unit flanked by a phenyl group and a short aliphatic c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  3.25E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Florida Research Foundation

US Patent
LigandPNGBDBM163635(SR-3298 | US10807944, Compound RLS2-225 | US117319...)
Affinity DataIC50:  1.67E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails US Patent