BDBM163638 1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2dihydroquinolin3yl)methyl]thiourea (Inh 3)

SMILES Cc1ccc2[nH]c(=O)c(CN(CCO)C(=S)Nc3ccccc3F)cc2c1

InChI Key InChIKey=WPRDQOPGGXWYOO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 163638   

TargetBeta-glucuronidase(Escherichia coli (Enterobacteria))
University of North Carolina At Chapel Hill

LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  680nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 無 assay buffer, 5 無 inhibitor solution, 5 無 of 10 nM enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-galactosidase [V151I,I185V](Clostridium perfringens (Firmicutes))
University of North Carolina At Chapel Hill

LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  7.80E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 無 assay buffer, 5 無 inhibitor solution, 5 無 of 10 nM enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Streptococcus agalactiae (Firmicutes))
University of North Carolina At Chapel Hill

LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  1.10E+4nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 無 assay buffer, 5 無 inhibitor solution, 5 無 of 10 nM enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed