BDBM164208 US9688615, 19

SMILES CC(C)(C)NC(=O)CN1CC(Cc2nc3c(cc(cc3[nH]2)C(F)(F)F)C(F)(F)F)C1

InChI Key InChIKey=KUPRRUQAZUUGQL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 164208   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  7.00E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  2.94E+3nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  4.5nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  3.56E+3nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  40nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  6.12E+3nMpH: 7.4Assay Description:To assess the potential cardiac liability of compounds at an early stage in the drug discovery process, a Nav1.5 sodium channel screening assay was b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Homo sapiens (Human))
SRMLSC

US Patent
LigandPNGBDBM164208(US9688615, 19)
Affinity DataIC50:  530nMAssay Description:Cells were plated in 384-well, clear-bottom, black-walled, poly-D-lysine coated plates (Becton Dickinson, Franklin Lake, N.J.) 2 days prior to use in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent