BDBM164883 US9067888, 33

SMILES COc1cc(F)ccc1-c1ccnc(NC(=O)[C@H]2CCC[C@H](C2)NC(C)=O)c1

InChI Key InChIKey=QNWXRLPZIFMTBK-DOTOQJQBSA-N

Data  21 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 164883   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant full length human N-terminal GST-fused CDK9 (1 to 372 residues)/His-tagged CyclinT1 (1 to 726 residues) expressed in baculo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  130nMAssay Description:Inhibition of CDK9 in human MCF7 cells assessed as reduction in RNA Polymerase 2 CTD phosphorylation at Ser2 residues measured after 6 hrs by immunof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataEC50:  220nMAssay Description:Inhibition of CDK9 in human MV4-11 cells assessed as induction of caspase-3/7 activation measured after 6 hrs followed by Caspase-glo reagent based a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed