BDBM164903 US10166239, Ex. 3-28::US11274108, Example 1-254::US11406644, Example 3-28::US9067914, Ex. 3-17::US9067914, Ex. 3-28

SMILES COc1ccc(COc2ccc(Cn3cnc4cc(cnc34)N3CCN(C)CC3)cc2OC)cn1

InChI Key InChIKey=IIJKGBMUSGQZJO-UHFFFAOYSA-N

Data  25 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 164903   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164903(US10166239, Ex. 3-28 | US11274108, Example 1-254 |...)
Affinity DataIC50:  179nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164903(US10166239, Ex. 3-28 | US11274108, Example 1-254 |...)
Affinity DataIC50:  66nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164903(US10166239, Ex. 3-28 | US11274108, Example 1-254 |...)
Affinity DataIC50:  179nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164903(US10166239, Ex. 3-28 | US11274108, Example 1-254 |...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164903(US10166239, Ex. 3-28 | US11274108, Example 1-254 |...)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164903(US10166239, Ex. 3-28 | US11274108, Example 1-254 |...)
Affinity DataIC50:  337nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent