BDBM165194 4‐Chloro‐7‐nitro‐3‐[(5‐phenylpentyl)oxy]isochromen‐1‐one (21)

SMILES [O-][N+](=O)c1ccc2c(Cl)c(OCCCCCc3ccccc3)oc(=O)c2c1

InChI Key InChIKey=VKSNRCDTOIDGQI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 165194   

TargetRhomboid domain-containing protein(Aquifex aeolicus (Aquificales))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid domain-containing protein(Pyrococcus horikoshii (Euryarchaeotes))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid domain-containing protein(Thermotoga maritima (Thermotogales))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  2.80E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlpG protein(Vibrio cholerae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  7.60E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid-related protein 3(Mus musculus (Mouse))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  2.40E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid protease GlpG(Haemophilus influenzae (g-Proteobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  4.60E+3nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid protease GluP [F193S,L370F,L379S,R499W](Bacillus subtilis (Firmicutes))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  2.50E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid-related protein 1(Mus musculus (Mouse))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  3.90E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRhomboid protease AarA(Providencia stuartii (Enterobacteria))
Technische Universität München

LigandPNGBDBM165194(4‐Chloro‐7‐nitro‐3‐[...)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed